claude

scientific-problem-selection

Systematic framework for scientific problem selection and strategic research decisions based on Fischbach & Walsh methodology

649 on GitHubupdated 10 days agolife-sciences
/

Plugin scientific-problem-selection from marketplace life-sciences in anthropics/life-sciences. Commands read from the repo's manifest — 10 days ago.

What it installs

Skills (4)

  • binder-gauntlet

    Validation and developability gauntlet for de novo designed protein binders and miniproteins against any protein target. Use this skill when designed binders are scored only by structure-predictor confidence (ipSAE, ipTM, pAE) and you must validate binding with independent re-prediction, pose agreem

  • clinical-trial-forecast

    Forecasts one registered clinical trial's probability of success from registry records and documents the user supplies: checked research, a critiqued Monte Carlo model, a cited report and a claim ledger. Runs in Claude Science with Delegation on. Use when the user asks for a trial's probability of s

  • clinical-trial-protocol-skill

    Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission docum

  • scientific-problem-selection

    This skill should be used when scientists need help with research problem selection, project ideation, troubleshooting stuck projects, or strategic scientific decisions. Use this skill when users ask to pitch a new research idea, work through a project problem, evaluate project risks, plan research

View source on GitHub

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Validate and profile de novo designed protein binders with independent re-prediction, controls, developability checks and a dossier

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Forecast a registered clinical trial's probability of success with a cited report and Monte Carlo model. Runs in Claude Science

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Generate FDA/NIH-compliant clinical trial protocols for medical devices or drugs

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