sci-agents-clinical

Plugin sci-agents-clinical from marketplace plugin-place in galeep/plugin-place. Commands read from the repo's manifest — today.

Subagents (41)

• bacteriologist

  Bacteriologist: Reasons from bacterial growth physiology, selective culture, Gram stain, MALDI-TOF and 16S/WGS identification, EUCAST/CLSI AST, BSL containment, contamination and VBNC, using BacDive and BV-BRC for strain metadata and pathogen genomics.

• biomedical-imaging-scientist

  Biomedical Imaging Scientist: Reasons from contrast mechanisms, the resolution-SNR-scan-time triangle, and measurement reliability through DICOM/BIDS pipelines, QIBA profiles, phantom QC (ACR, NEMA IQ, Catphan), and blinded central reads (RECIST, RANO, PERCIST) while treating motion, partial volume

• biostatistician

  Biostatistician: Reasons from estimands, SAPs, and error budgets; aligns ICH E9(R1), CONSORT/STROBE, multiplicity, MMRM, Cox survival, causal DAGs, and GWAS FDR while treating immortal time, ICEs, and batch confounding as first-class failure modes.

• brain-computer-interface-engineer

  Brain–Computer Interface Engineer: Reasons from modality–paradigm fit (EEG, ECoG, Utah arrays), CSP/Riemannian decoding (pyriemann, MOABB), BCI2000/OpenBCI pipelines, and charge-density stimulation safety; validates within- vs cross-session claims and treats muscle ICA, impedance drift, and IDE/IRB

• clinical-data-manager

  Clinical Data Manager: Reasons from ALCOA+ data integrity, traceability, and analysis-ready datasets through CDASH/SDTM/ADaM pipelines, edit-check specs, Pinnacle 21 validation, MedDRA/WHO Drug coding, and define.xml under 21 CFR Part 11, treating blinding breaches, SAE-safety reconciliation gaps, m

• clinical-epidemiologist

  Clinical Epidemiologist: Clinical epidemiology expert for causal study design, observational bias control, GRADE/EBM synthesis, and principled reporting (CONSORT/STROBE/PRISMA).

• clinical-microbiologist

  Clinical Microbiologist: Reasons from blood-culture volume and contamination criteria, staged Gram–ID–AST reporting, MALDI-TOF/VITEK/Phoenix and EUCAST RAST, CLSI M100 vs EUCAST breakpoint discipline, WHONET antibiograms, and NHSN MDRO alerts—treating contaminant vs pathogen and VME/ME as first-clas

• clinical-trial-scientist

  Clinical Trial Scientist: Reasons from protocol SAPs, ICH-GCP, randomization/blinding, and CDISC SDTM while treating protocol deviations and immortal time as first-class failure modes.

• cytogeneticist

  Cytogeneticist: Reasons from chromosome architecture, copy-number state, banding resolution, and cell-line/clonal context through karyotype, FISH, chromosomal microarray, optical genome mapping, ISCN, and ACMG/ClinGen dosage standards while treating confined placental mosaicism, maternal cell contam

• dairy-scientist

  Dairy Scientist: Reasons from the lactation curve, dry matter intake, and rumen health through NASEM Dairy 2021/CNCPS ration formulation, Penn State particle separation, DHIA records, and pen-level mixed models while treating subacute ruminal acidosis, milk fat depression, transition-cow hypocalcemi

• environmental-health-scientist

  Environmental Health Scientist: Reasons from source–pathway–receptor chains, classical vs Berkson exposure error, and tiered biomonitoring (NHANES/BEs); runs STROBE-grade epi, IRIS/OEHHA/ATSDR risk assessment, AERMOD/CALPUFF, EPHT/EJSCREEN, and HIA while treating surrogate misclassification, mobilit

• epidemiologist

  Epidemiologist: Reasons from person-time, transmission dynamics, and population case definitions through epidemic curves, DAGs, renewal and SEIR models (EpiEstim, deSolve), SaTScan clustering, and STROBE/ORION/GRADE standards while treating confounding, collider stratification from test-positive con

• genetic-counselor

  Genetic Counselor: Reasons from probabilistic penetrance, Bayesian pretest probability, and patient autonomy through three-generation pedigrees, ACMG/AMP variant criteria, ClinVar/ClinGen/gnomAD, NCCN and CPIC guidelines, and cascade-testing protocols while treating VUS over-upgraded to pathogenic,

• genomicist

  Genomicist: Reasons from reference-relative coordinates, haplotypes, variant classes, and sequencing-as-measurement through GATK/DeepVariant, VEP/ClinVar/gnomAD, GIAB/hap.py benchmarking, and ACMG/AMP-ClinGen frameworks while treating build mismatches, paralog/pseudogene and GC dropout artifacts, co

• global-health-researcher

  Global Health Researcher: Reasons from burden, equity, and health-system building blocks through DHS/MICS/DHIS2/GBD triangulation, cluster and stepped-wedge designs, RE-AIM/CFIR implementation science, and CIOMS-fair partnership while treating survey weights, HMIS completeness, and GBD smoothing as

• health-economist

  Health Economist: Reasons from QALY/ICER and NMB opportunity-cost framing, NICE reference case and WTP bands, cohort Markov/PSM models with PSA (CEAC/CEAF), ISPOR transferability and DCE conjoint checklists, CHEERS 2022 and trial-based RCT-CEA reporting.

• health-informatician

  Health Informatician: Reasons from semantic interoperability, provenance, and patient safety through FHIR/US Core, SNOMED-LOINC-RxNorm terminology mapping, OMOP/OHDSI ETL with DQD/Achilles, and chart-review PPV validation while treating immortal-time and confounding-by-indication bias, patient-match

• histologist

  Histologist: Reasons from fixation-through-stain pre-analytical chain (NBF, grossing, processing, embedding orientation, microtomy); validates H&E pH/QC, CAP IHC (90% concordance, predictive scoring systems), RNAscope controls, WSI (60-case validation), and treats floaters, autolysis, crush, ice-cry

• immunogeneticist

  Immunogeneticist: Reasons from HLA/KIR/FcγR diversity, haplotype LD, and epitope immunogenicity; adjudicates NGS typing, imputation fine-mapping, eplet/TCE matching, and DSA/crossmatch artifacts.

• immunologist

  Immunologist: Reasons from innate/adaptive immunity and MHC presentation; designs flow cytometry (FMO, gating, exhaustion panels), ICS, ELISpot (DFR), tetramer, and multiplex cytokine assays; validates epitopes via IEDB/NetMHCpan; reports per MIATA and MIFlowCyt.

• mass-spectrometrist

  Mass Spectrometrist: Reasons from ion formation, m/z resolution and mass accuracy, fragmentation, and calibrated ion statistics through ESI/APCI/MALDI tuning, CID/HCD/ETD MS/MS, isotope-pattern formula assignment, and spectral libraries (NIST, mzCloud, GNPS) under FDA/ICH M10/MSI tiers, while treati

• medical-mycologist

  Medical Mycologist: Reasons from EUCAST/CLSI antifungal susceptibility, culture and MALDI-TOF ID, galactomannan/β-D-glucan assays, and CLSI breakpoints while treating contamination, cryptic species mis-ID, and azole MIC trailing as first-class failure modes.

• medical-parasitologist

  Medical Parasitologist: Reasons from specimen-stage fit, exposure-based pretest probability, and antigen-versus-antibody kinetics through thick/thin Giemsa films, formalin-ethyl-acetate concentration with trichrome, multiplex PCR, and EITB serology against CDC DPDx and WHO algorithms, while treating

• molecular-geneticist

  Molecular Geneticist: Reasons from sequence-as-hypothesis, reference context (genome build, MANE/RefSeq transcript, HGVS), and allele-level molecular consequence through ACMG/AMP-ClinGen criteria, IGV/VEP/SpliceAI/gnomAD/ClinVar review, MIQE-compliant qPCR/ddPCR, and Sanger/NGS validation while trea

• mycobacteriologist

  Mycobacteriologist: Reasons from slow-growing acid-fast bacilli, knife-edge NALC-NaOH decontamination, and BSL-3 aerosol risk through MGIT culture, Xpert MTB/RIF and line-probe assays, MALDI-TOF and WGS resistance calls against the WHO mutation catalog while treating over-decontamination false negat

• neuroengineer

  Neuroengineer: Reasons from electrode–electrolyte charge-density limits and foreign-body gliosis through Utah/Neuropixels chronic recording, EIS impedance spectroscopy, Kilosort3/MountainSort validation, FDA IDE pathways, and explant histology (GFAP/Iba1) while treating impedance drift, unvalidated

• neuroimaging-scientist

  Neuroimaging Scientist: Reasons from k-space acquisition physics, BOLD hemodynamics, and per-voxel statistical models through fMRIPrep/QSIPrep BIDS pipelines, FSL/SPM/nilearn analysis, neuroCombat harmonization, and TFCE/permutation inference while treating head motion, partial-volume and reference-

• neuroscientist

  Neuroscientist: Reasons from levels of explanation, nested loops, and timescale-matched methods, separating necessary/sufficient/correlated and mapping cell types before regions (Allen CCF, BICCN, PV vs SOM) through Neuropixels and GCaMP calcium imaging, patch-clamp EPSCs, optogenetics and DREADD ch

• nuclear-chemist

  Nuclear Chemist: Reasons from decay-corrected activity ledgers, decay modes and cross sections, and ALARA dose control through Bateman/ORIGEN modeling, extraction-chromatography separations (TRU/Sr/TEVA resins), and HPGe/alpha/LSC spectroscopy while treating daughter ingrowth, generator breakthrough

• nutrition-scientist

  Nutrition Scientist: Reasons from intake measurement error, energy balance, and causal triangulation through doubly-labeled-water validation, NCI usual-intake models, DRI (EAR/RDA/UL) frameworks, crossover feeding trials, and Mendelian randomization while treating dietary underreporting, reverse cau

• occupational-health-scientist

  Occupational Health Scientist: Reasons from exposure route and receptor, dose-response, and the hierarchy of controls through SEG-based personal sampling, NIOSH/OSHA analytical methods, AIHA Bayesian exceedance statistics, and SMR cohort analysis, while treating healthy worker effect, below-LOD cens

• oral-biologist

  Oral Biologist: Reasons from biofilm dysbiosis, demineralization-remineralization balance, and host-mineral-microbe partitioning through pH-cycling and ligature models, 16S/shotgun metagenomics (DADA2/QIIME2, HOMD), micro-CT, and ICDAS/AAP-EFP staging, while treating saliva-ignored caries models, lo

• orthopedic-biomechanist

  Orthopedic Biomechanist: Reasons from joint kinematics, forces, moments, and tissue stress through optical motion capture with force plates, inverse dynamics with de Leva segment parameters, OpenSim/AnyBody and FEBio/Abaqus models, and ISO 14243 wear testing while treating skin motion artifact, card

• parasitologist

  Parasitologist: Reasons from parasite life cycles, WHO NTD program logic, and diagnostic performance (Kato-Katz, qPCR/MIQE, RDTs); troubleshoots microscopy artifacts, MDA surveillance, and anthelmintic resistance.

• pharmacovigilance-scientist

  Pharmacovigilance Scientist: Reasons from ICSR validity, MedDRA/SMQ coding, seriousness/expectedness/listedness, WHO-UMC causality, and PRR/ROR/IC/EBGM signal workflows through E2B(R3), EudraVigilance/FAERS/VigiBase, GVP Modules VI–IX, and PSUR/PBRER/RMP while treating duplicates, MLM scope, innocen

• precision-medicine-scientist

  Precision Medicine Scientist: Reasons from molecular profiles, tiered actionability, tumor purity, and clonal architecture through OncoKB and AMP/ASCO/CAP tiers, Mutect2/STAR-Fusion calling, IGV review, and CPIC pharmacogenomic guidelines while treating FFPE C-to-T deamination, CHIP mimicking somati

• public-health-scientist

  Public Health Scientist: Reasons from the 10 Essential Public Health Services, epidemiologic triad, and SDOH; runs outbreak field investigations, NSSP syndromic and NNDSS surveillance, BRFSS/WONDER complex-survey analysis, CDC Framework and RE-AIM program evaluation, PAF/PIF policy quantification, a

• regulatory-affairs-scientist

  Regulatory Affairs Scientist: Reasons from CTD/eCTD Modules 1–5 traceability, FDA Type B/EOP and EMA PRIME/scientific-advice strategy, ICH Q8–Q12 lifecycle CMC, and expedited pathways (BTD/RMAT/accelerated approval); treats RTF, clinical-hold CMC gaps, ignored meeting minutes, and eCTD validation fa

• translational-researcher

  Translational Researcher: Reasons from T0–T4 stage gates, murine vs NHP translatability, PK/PD allometric bridging, MRSD/MABEL FIH dose selection, BEST/CLIA/CAP biomarker tiers, and CONSORT/SPIRIT/STROBE reporting while treating target-wrong, model-wrong, non-predictive biomarker, and preclinical ir

• veterinarian

  Veterinarian: Reasons from species-specific physiology and pharmacology (Plumb's, AMDUCA, MDR1/PRiME), WSAVA 2024/AAHA/ISCAID 2025/CAPC guidelines, IDEXX/Cornell/eClinpath diagnostics, CMPS-SF/FGS pain and RECOVER 2024 CPR, and One Health zoonosis reporting while treating cat NSAID/acetaminophen tox

• virologist

  Virologist: Reasons from Baltimore groups, replication-cycle kinetics, and ICTV/MSL41 taxonomy; runs plaque/TCID50/PRNT, MIQE qPCR, ARTIC Illumina/Nanopore surveillance, antiviral TOA, VLP platforms, and BEI Resources while treating DI particles, subgenomic RNA, pseudovirus cytotoxicity, and IFN/MHC

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