Read-only access to Tahoe's single-cell perturbation data through the Tahoe public tools, for drug-discovery research. Look up covered drugs, doses, cell lines and genes; read drug annotations (targets, mechanism of action, approval status); and retrieve expression, drug-versus-vehicle differential expression, perturbation markers, pathway scores and embedding distance from vehicle. Read the validated signature readout for a cancer process: one per process, where one exists, in one dataset only. Compare a compound's response with annotated mechanism classes; compare drug responses between genotype- or lineage-defined groups of cell lines; correlate a cell line's baseline expression or driver-gene status with its drug response (exploratory); and rank drug-induced relative depletion and cell-cycle effects per cell line across three doses. Includes guarded read-only SQL and analysis guidance. Requires a Tahoe account; available datasets and capabilities depend on the account.
Plugin tara from marketplace tahoe-public in tahoebio/tahoe-public-plugins. Commands read from the repo's manifest — 6 days ago.
taraRead-only access to Tahoe's data through the Tahoe public tools. Use for drug-discovery analyses of large-scale single-cell perturbational transcriptomics: phenotypic profiling, mechanism-of-action inference, and pathway-response and cell-state analysis.
tahoe-publicconnects to: https://tara.tahoebio.io/mcp
General life-sciences research workflows with query routing, evidence synthesis, and optional parallel subagent analysis across genetics, omics, biology, chemistry, structure, clinical evidence, and public dataset discovery.
50 skills
Cross-profession skills: Press Release, Grant Proposal, Executive Summary, Teaching Lesson Plan, Sycophancy Challenger, Last 30 Days Research, NotebookLM Connector, Professional Brain, Action Runner. Get genuine push-back on your ideas, gather multi-platform research, automate NotebookLM — plus the Professional Brain: a durable local memory skills read & write back (provenance-tagged), and Action Runner to execute a skill's recommendations (open tickets, post updates) safely behind a dry-run approval gate.
11 skills
Twelve-skill bundle covering the Review of Educational Research (RER) review-article lifecycle, from scoping a synthesis-worthy question and a preregistered protocol through systematic search, the organizing framework, comprehensiveness and risk-of-bias, PRISMA/MARS transparency, submission, and revision.
12 skills
A gated mathematical-modeling contest workflow with human-owned decisions and submission audits.
29 skills · hooks
Edit mathematically, empirically, or technically dense papers for readers outside the author’s specialty, including empirical legal scholarship, law-and-economics models, and legal-technology research. Clarifies terminology, antecedents, study design, and claim–statistic relationships while checking equations, numbers, quotations, and citations against the source. Use to clarify exposition or de-jargonize a technical draft; not to rewrite briefs or doctrinal arguments. Produces an edited draft and audit memo. Full integrity checks and original-format rendering require suitable extraction, code execution, and document tools; otherwise provides proposed edits with verification limits disclosed.
200 skills
Pair programming protocol for marimo notebooks
2 skills
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